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Improve Cardiovascular Health With Us

Northern Bio offers specialized expertise and cutting-edge technologies to accelerate the development and evaluation of therapies for heart and vascular diseases to provide robust data and compliance in the preclinical stage of therapeutic development in cardiology.

Advance Cardiac Therapeutics

Northern Bio offers services to support the many therapies addressing heart and vascular diseases. This may be inclusive of acute myocardial infarction, congestive heart failure, coronary artery disease, arrhythmias, hypertension, and atherosclerosis, amongst others. By leveraging state-of-the-art imaging and biomarker assessment and utilizing specified preclinical approaches, Northern Bio is able to accelerate programs from concept to regulatory approval.
scientist using lab computer

Consult a Scientist

We are a team of scientists who value open communication and collaboration. We work closely with our sponsors to provide customized solutions and expert support.

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Targeted Delivery

Northern Bio supports the development of diverse therapeutic modalities, including biologics, gene therapies (AAVs), RNA-based treatments, and small molecules. Targeted delivery approaches such as epicardial injection, catheter-based endocardial delivery, coronary artery delivery, and standard intravascular infusion approaches to assess toxicological and efficacious effects in order to promote better patient outcomes.

Instrumentation & Capabilities

Equipment

MRI – Philips 3T
Philips Intellispace Image Analysis
2 GE OEC9900 Cardiac Fluoroscope
Philips CVx ultrasound
Include 3D probes for automated strain and heart structure analysis
Visualsonics Vevo
Jacketed and Implantable Telemetry

Cardiac Injury Models

Acute Myocardial Infarction (Ischemia-Reperfusion Injury)
Congestive Heart Failure
Critical Limb Ischemia
Peripheral Artery Disease/Atherosclerosis
HFpEF

Routes of Administration

Epicardial
Endocardial
Retrograde Coronary Sinus
Coronary Artery Delivery
Intravenous
Intra-arterial

Species

Mouse
Rat
Rabbit
Canine
NHP
Swine
Sheep

Frequently Asked Questions (FAQs) about Cardiovascular

Northern Bio supports all of the most common species of animals when assessing cardiovascular therapies. While not limited to, the most common species utilized for these studies are rodents, canines, swine, and nonhuman primates.

Partner With Us

Let’s work together to develop
life-changing treatments.

Join us in the pursuit of better lives through scientific innovation. Explore how Northern Bio can help you achieve your research goals.

CONSULT A SCIENTIST