BETTER LIVES BEGIN HERE

At Northern Bio, better lives begin with science. We are a team of passionate researchers driven by a common purpose: to develop treatments and cures for devastating diseases and improve human and animal health.

Innovative Treatments Begin With Us

Northern Bio is a preclinical CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis to develop safe and effective treatments for devastating diseases. Using advanced surgical techniques and research, we maximize therapeutic impact. Collaboration and open communication are key to the strong partnerships we have with our sponsors. Committed to excellence, Northern Bio transforms possibilities into reality, paving the way for better lives through rigorous research and scientific advancement.

Advance Your Research With Us

Northern Bio specializes in preclinical research services, with expertise in in vivo non-GLP and GLP safety assessment solutions for novel therapeutics using advanced surgical techniques. Our Bioanalysis group focuses on advanced molecular biological techniques and ligand binding assays. We collaborate closely with our clients to develop customized preclinical studies to facilitate regulatory approval.

Committed to Animal Welfare

At Northern Bio, we are devoted to the welfare of the laboratory animals in our care. We have the utmost compassion and respect for our animals. The extensive training that our staff receives supports the unwavering dedication to the principle of the 3Rs (replacement, reduction, and refinement). This refined approach safeguards the quality of life of the animals and ensures the success of your study.

Change the World With Us

At Northern Bio, we’re not just conducting research; we’re changing the world, one experiment at a time. Join our team and contribute to groundbreaking research that has the power to transform lives.

Latest Blog Posts

White Papers

qPCR and qRT-PCR analysis: Regulatory Points to Consider When Conducting Biodistribution and Vector Shedding Studies

Gene and cell therapy fields have experienced remarkable growth during the past decade. Demands for preclinical and clinical safety assessments of these cell and gene therapy test articles (TAs) have ...
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Webinars

Triplex RT-dPCR Method for a Safety Study in Drug Development

Gene expression analysis is typically completed for various safety and efficacy studies to complement drug development for viral and non-viral vector therapeutics. Currently, there is no definitive guidance for this ...
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Posters

Route to a Safe Delivery Strategy of AAV-Based Gene Therapy to the Caudate and Putamen of Nonhuman Primates

Adeno-associated virus (AAV) is an effective platform for delivering genetic medicines to the brain via multiple routes, including direct brain infusion, cerebrospinal fluid (CSF) compartment infusion, or intravenous infusion. SPK-10001 ...
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Posters

SPK-10001 Induces a Durable and Safe Reduction of HTT Protein Supporting Further Development in Huntington’s Disease

SPK-10001, an AAV-based gene therapy for Huntington’s disease (HD), targets Huntingtin protein (HTT) accumulation in the brain’s basal ganglia. Administered via bilateral intraparenchymal (IP) infusion using MRIguided ClearPoint SmartFlow cannula, ...
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Posters

Melanosis of the Dentate Nucleus in Two Cynomolgus Macaques

Melanin deposits occasionally occur in central nervous system tissues. In cynomolgus macaques, spontaneous perivascular melanin pigment occurs in the meninges and in the cerebral cortex. Additionally, neuromelanin pigment accumulates with ...
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Posters

Discovery of a Novel C3-Targeting and CNS Active siRNA as a Potential Therapeutic for Alzheimer’s Disease

Complement component C3 plays a central role in neuroinflammation and synaptic dysfunction in Alzheimer’s disease (AD), making it a compelling therapeutic target. Here, we describe the discovery and characterization of ...
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Upcoming Events

Upcoming Events

American College of Toxicology (ACT) 2025, Phoenix

American College of Toxicology (ACT) 2025 Meeting

November 16, 2025
The American College of Toxicology brings together professional scientists from around the globe to advance applied toxicology. Our members represent…
Keystone Symposia

Obesity Therapeutics: Unlocking Benefits and Minimizing Side Effects

January 26, 2026
Obesity, a leading cause of human morbidity and mortality, is one of the major global health challenges of the 21st…
Association for Research in Vision and Ophthalmology (ARVO) 2026, Denver

The Association for Research in Vision and Ophthalmology (ARVO) 2026 Meeting

May 3, 2026
The ARVO Annual Meeting is the premiere gathering for eye and vision scientists from across the globe, at all career…

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Let’s work together to develop
life-changing treatments.

Join us in the pursuit of better lives through scientific innovation. Explore how Northern Bio can help you achieve your research goals.