Customize Surgical Models With Us

Northern Bio offers cutting-edge surgical models and develops procedures in support of medical devices and targeted delivery across different therapeutic areas. The surgical capabilities are designed to cater to the customization and setup needed to advance the development of your therapeutic.

Enhance Your Preclinical Studies

Northern Bio offers a range of surgical models for use in medical device evaluation, efficacy/pharmacology studies, and safety assessment. Our research scientists and surgeons have extensive experience in the development of sophisticated surgical procedures in small and large animal species. Our team partners with you to assist in creating the most relevant animal model for an enhanced understanding of your compound.

Consult a Scientist

We are a team of scientists who value open communication and collaboration. We work closely with our sponsors to provide customized solutions and expert support.

Targeted Delivery

Northern Bio supports the development of diverse therapeutic modalities, including biologics, gene therapies (AAVs), RNA-based treatments, and small molecules. Targeted delivery approaches, such as intravitreal, intracameral, intracorneal, subretinal, suprachoroidal, and topical administrations, ensure precise delivery to specific ocular tissues for toxicological and efficacious assessment.

Instrumentation & Capabilities

Routes of Administration

Intrahepatic
Intra-articular
Direct cartilage and tendon
Long bone, spinal, and craniofacial implant
Direct intestinal
Intravesicular (bladder)
Retrograde renal
Organ-specific
Intraprostatic

Surgical Models

Intrathecal device implantation
Epidural device implantation
Intracranial device implantation
Stereotaxic administration
Stroke
Parkinson’s disease
Renal ischemia-reperfusion injury
Partial nephrectomy for evaluating hemostasis
Hemostasis models – Liver and spleen
Full thickness excision
Full thickness incision
Burn wounds
Bacterial infection (up to BSL2)
Scar formation

Species

Mouse
Rat
Rabbit
Canine
NHP
Swine
Sheep

Partner With Us

Let’s work together to develop
life-changing treatments.

Join us in the pursuit of better lives through scientific innovation. Explore how Northern Bio can help you achieve your research goals.